There are separate Houses for boys and girls. All First Year boys go into one of two junior Houses. At the end of their First Year, boys will express a preference for the friends they would like to have with them in a senior House, to which they are promoted for their remaining four years. Girls are in the same House throughout their time in the School, the two systems being designed in the light of experience.

During their junior years, pupils share bedroom and study accommodation with several others; lower Sixth Form accommodation is in double study bedrooms and all upper Sixth Formers have their own rooms.

All Houses have a social area and small kitchens for making hot drinks and snacks. Each House is in the care of a housemaster or housemistress (known at Bryanston as a 'hsm'), who is assisted by a matron, a team of teaching staff and House prefects.

Hsms are important figures in the lives of the pupils, but Houses do not carry the intense 'tribal' loyalties that sometimes exist in schools whose social arrangements are based on a strong House tradition. Bryanston is essentially a school, not a federation of separate Houses and pupils are encouraged to become fully involved in the caring atmosphere of the extended Bryanston family, in which the older boys and girls are frequently to be seen working with and helping youngsters.